Weir will be making her international debut on the track and will compete in the women’s steeplechase.
The Birmingham University student enjoyed a highly successful cross country season and represented Great Britain in the junior women’s races at both the European and World Cross Country Championships.
King will be England’s representative in the 110m hurdles at the event, which will take place on May 21.
Loughborough has proved a fast track for the sprint hurdles in the past and King, who competed for Great Britain at the last European outdoor and indoor championships, will be hoping to post a good early season time.
England will take on teams from Scotland, Great Britain & NI Juniors, Wales, Loughborough Students, and British Universities.