The Pilgrims are due to visit Chichester City in the National League Southern Premier Division.
Argyle do not have a good record against Chichester. In the 2016-17 season, Chichester completed the double (5-4) and (3-0) to win Division One South West with Argyle second.
The following campaign, Argyle beat them 3-1 in the Premier League Cup, but last season Chichester complete the double again over the Pilgrims (3-0) and (2-1).
The West Sussex side may be bottom of the league but they only went down 3-2 at home to league leaders Watford last week so Argyle will not go into the match expecting an easy game.
The Pilgrims do head to Chichester on the back of a seven-match league and cup winning run.
“We had a full compliment at training so we will be taking a fully fit squad to Chichester,” said manager Dave Leonard. “We are looking forward to the game and getting back to our league form. The girls are really looking forward to it.”
He added: “I have never beaten them. In fact, I’ve never taken a point off them.
“We had them watched last weekend (against Watford) and on their performance they are in a bit of a false position so we are under no illusions. They don’t deserve to be bottom of the league and form tables have a habit of kicking you up the backside.
“It’s not going to be an easy game. It’s not a game I would like to have had having not played for the last three weeks.”
Leonard was happy with the National League Plate draw where Argyle will host AFC Wimbledon in the second round. That tie on Sunday, November 24 has been moved to Marjons (12 noon kick-off).
“I am absolutely delighted,” said Leonard. “I don’t care who we have, it just needed to be a home draw.
“We are looking at this and thinking we can do something in this cup and it’s something we are going to try and win. All we want now is a nice home draw in the FA Cup on Monday.”
Argyle squad to face Chichester: B Kyle, L Burridge, E Dover, B Jackson, L Huntley, F Ivall, J Jones, A Pollock, K Lane, B Dandridge, S Beck, Z Cunningham, N Knapman, H Bleazard, K Middleton, M Taylor.
Meanwhile, Argyle’s development team also face a difficult match in the South West League Western Division when they play Plympton at Bull Point (2pm).
In the 2017-18 season, Plympton won 2-1 and drew 1-1, while last season despite Argyle winning the division, Plympton beat Argyle 3-2 while the Greens fought back from 3-0 down to draw the home match 3-3. That draw left Plympton having to settle for runners-up spot. Plympton also beat Argyle 2-1 at the beginning of the season.
Argyle, who were without a fixture last week, are in a confident mood after some outstanding wins recently. But manager Rob Bonney is trying to keep the team grounded.
He said: “This is still a team in transition but the expectation levels are rising game by game. The results are there for people to see but what we (coaches Scott Robertson and Dan Tecza) want to see is a rise in our performance levels. There is still more to come and it is a case of instilling even more confidence and getting the players to perform to the maximum of their capabilities.”
Argyle development squad (from): Maddie Walsh, Rachel Javan, Isla Brumhead, Hannah Brock, Rachel Heron, Beth Cowd, Maisie Williams, Ellie Bishop, Beth Everson, Lucy Solloway, Nicola Champion, Dani Wyatt, Kiara Robins, Dee Newman, Maddy Leppard, Chardonnay James, Scarlett Williams.