The event will take place in the German capital between August 20 and August 26.
City of Plymouth athlete Arnott will compete in the T47 100m and 200m.
His selection comes on the back of winning silver for England in the 100m at the Commonwealth Games in Australia in April.
He will be joined in the Great Britain team by seven world champions, including Hannah Cockroft and Richard Whitehead.
Paula Dunn, head coach at British Athletics, said: “I am delighted to announce the 52 athletes selected to compete for Great Britain & Northern Ireland at the World Para Athletics European Championships in Berlin in August.
“We have a great tradition of winning medals at a continental level and I am looking forward to watching how our experienced athletes and those making their debuts perform.
“After a three-year period involving two World Championships, a Europeans and a Paralympic Games, it was always the intention for a handful of athletes to rest and recuperate in 2018.
“We have a great mixture of athletes going to Berlin who have reached the very top of the sport and those beginning their journey and I’ve no doubt they will learn a lot from each other in Berlin.”