As Plymouth Sports Gazette has previously reported, the pair have been training with each other for the past few months in the hope of securing Great Britain a synchro spot at this summer’s Olympic Games in Rio.
Final qualification for the Olympic places will take place at next month’s World Cup in Rio.
Goodfellow, 19, has missed the bulk of the last two seasons due to injury, but is now fully fit and ready to get his promising career back on track.
Plymouth Diving’s Tonia Couch will also debut a new synchro partnership this weekend in Southend.
She will dive with Leeds’ European Games teenage champion Lois Toulson, instead of her long-standing partner Sarah Barrow.
National performance director Alexei Evangulov said: “The British National Diving Cup is going to be a strong competition and a good opportunity to see where the athletes are ahead of what will be a busy year.
“We have two new synchro pairs and I have been happy with how they have trained together.”
Daley, who has not competed at synchro since the 2014 Commonwealth Games, said: “It’s been good training with Dan and I think that it’ll be exciting to get out and do synchro again.”
Plymouth Diving have 15 athletes competing in Southend. The event takes place between Friday and Sunday.