Plymouth-born Daley finished nearly 80 points ahead of second-placed Matty Lee, despite dropping his second dive.
Daley scored 507.95 points, having collected 549.10 points in the morning’s prelims.
The former World champion said: “There were a few dives in the final that I could have done better but overall I’m pretty happy overall with how it went.
“I was diving solidly in the prelims, maybe even better than in my European Championships performance.
“There were a few things that I actually corrected in the final as last year my arm-stand and my reverse were two of my weaker dives that I would never have been able to score tens on so, to do that today is really handy at this time of the year.”
Plymouth Diving’s Matthew Dixon finished fourth in the final with 372.80 points, having scored 382.60 in the prelims. His club team-mate Aidan Heslop was seventh in the final, scoring 270.50 points.