The Devils have had a mixed start at home, beating Somerset but losing to Peterborough last Friday.
Co-promoter Ashley Taylor says: “We will be looking for our riders to face up against Rye House and show that we can be strong at home.”
Luke Chessell, who rode for the Devon Demons in the National League last season, deputises for injured reserve Sam Chapman.
Rye House will be without Nikolaj Jakobsen, who is competing in the Danish Final of the World Under-21 Championships and operate rider replacement to cover his absence.
They are forced to bring in a couple of guests at reserve with Oliver Greenwood, who scored six (paid seven) for Peterborough last Friday, covering for Luke Bowen, who is withholding his services, while Glasgow’s James Sarjeant deputises for the injured Kasper Lykke.
Plymouth: Ryan Fisher, Sam Simota, Jack Holder, Morten Risager, Kyle Newman. Reserves: Ashley Morris, Luke Chessell.
Rye House: Edward Kennett, rider replacement for Nikolaj Jakobsen, Anders Mellgren, Steve Boxall, Robin Aspegren. Reserves: Oliver Greenwood, James Sarjeant.
PLYMOUTH suffered an injury blow in their League Cup match at Ipswich on Thursday evening when skipper Kyle Newman had to pull out with an elbow injury after a fall in his first ride.
Ipswich were also handicapped by an injury to Gino Manzares but went on to win 57-33.
Ryan Fisher top scored with 10 points for the Devils while former Ipswich man Morten Risager finished with nine (paid 10) from his five outings.
Ipswich: Danny King 15 (5 rides), Ritchie Hawkins 3 (4), Gino Manzares 0 (1), Cameron Heeps 5+1 (4), Rohan Tungate 12+1 (5). Reserves: Stefan Nielsen 10+1 (6), Nico Covatti 12+3 (5).
Plymouth: Ryan Fisher 10 (5), Sam Simota 2+1 (4), Jack Holder 4+1 (4), Morten Risager 9+1 (5), Kyle Newman 0 (1). Reserves: Ashley Morris 8 (6), Dan Halsey 0 (3).